Question 335 · LEK · Esophageal cancer

A 61-year-old male presents at the outpatient unit due to gradually worsening difficulty swallowing, initially solids, then also liquids. Additionally, he reports 6 kg weight loss over 3 months and weakness. In history: smoking (20 pack-years), moderate alcohol consumption. Physical examination is unremarkable. Indicate the appropriate management:

  1. A. start treatment with proton pump inhibitors (PPIs) and observation for the next 3 months.
  2. B. esophagogastroscopy (EG) with possible biopsy for histopathology.
  3. C. barium swallow X-ray of the oesophagus.
  4. D. oesophageal manometry and pH-metry to assess for gastroesophageal reflux. 114 z 117 29.06.2026, 14:15 Centrum Egzaminów Medycznych https://test.cem.edu.pl/pytcem/wyswietl_baza_pdf.php
  5. E. dietary recommendations, no need for further diagnostics.
Hint

Progressive dysphagia (solids then liquids) with weight loss in a smoker is an alarm picture; which test both visualises and gives tissue?

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