Question 338 · LEK · Gastric cancer

A 65-year-old male presents at the Emergency Department due to 10 kg weight loss over 3 months, loss of appetite, and fullness sensation after small meals. Gastroscopy revealed an ulcerated tumour in the prepyloric part of the stomach; histopathology examination confirmed adenocarcinoma. Abdominal CT revealed no distant metastases; endosonography (EUS) revealed that the tumour infiltrated the submucosa and partially the muscle layer, regional lymph nodes are suspicious (cN1). Indicate the appropriate management: 115 z 117 29.06.2026, 14:15 Centrum Egzaminów Medycznych https://test.cem.edu.pl/pytcem/wyswietl_baza_pdf.php

  1. A. only palliative chemotherapy.
  2. B. endoscopic mucosal resection or submucosal dissection (EMR/ESD).
  3. C. only radiotherapy as a radical method.
  4. D. gastrectomy with D2 lymphadenectomy, preceded by perioperative chemotherapy.
  5. E. treatment with proton pump inhibitors and, after ulcer healing, reassessment of tumour stage.
Hint

The tumour is locally advanced (muscle invasion, suspicious nodes) but non-metastatic; consider the multimodal curative approach.

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