KROK 1 2010 – Question 183 · KROK (Medicine) · Pathomorphology

A 23 year old man has perforation of hard palate. In the area of this perforation there was a compact well-defined formation. Microscopic examination of the resected formation revealed a large focus of caseous necrosis surrounded by granulation tissue with endovasculitis, cellular infiltration composed of lymphocytes, epithelioid cells (mainly plasmocytes). What is the most probable diagnosis?

  1. A. Leprosy
  2. B. Scleroma
  3. C. Syphilis
  4. D. Tuberculosis
  5. E. Sarcoma
Hint

Look at the cell types in the infiltrate and the vascular changes next to the necrosis, and ask which chronic infection gives this pattern in the palate.

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