KROK 1 2010 – Question 109 · KROK (Medicine) · Biological Chemistry

During hypersensitivity test a patient got subcutaneous injection of an antigen which caused reddening of skin, edema, pain as a result of histamine action. This biogenic amine is generated as a result of transformation of the following histidine amino acid:

  1. A. Deaminization
  2. B. Decarboxylation
  3. C. Isomerization
  4. D. Methylation
  5. E. Phosphorylation
Hint

Recall the general type of reaction by which an amino acid is turned into the corresponding biogenic amine in tissues, as also happens with serotonin and dopamine.

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