KROK 1 2009 – Question 178 · KROK (Medicine) · Biological Chemistry
A newborn child was found to have reduced intensity of sucking, frequent vomiting, hypotonia. Urine and blood exhibit increased concentration of citrulline. What metabolic process is disturbed?
- A. Glyconeogenesis
- B. Tricarboxylic acid cycle
- C. Glycolysis
- D. Ornithinic cycle
- E. Cori cycle
Hint
Ask in which metabolic pathway citrulline appears as an intermediate and what toxic nitrogen-containing substance would build up if that pathway were blocked in a newborn.
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