KROK 1 2009 – Question 194 · KROK (Medicine) · Biological Chemistry
Pharmacological effects of antidepressants are based upon blocking (inhibiting) the enzyme that acts as a catalyst for the breakdown of biogenic amines noradrenalin and serotonin in the mitochondria of cephalic neurons. What enzyme takes part in this process?
- A. Lyase
- B. Transaminase
- C. Peptidase
- D. Decarboxylase
- E. Monoamine oxidase
Hint
Think about what type of reaction breaks down amine neurotransmitters inside mitochondria, and how blocking that step would raise their level in the nerve terminals.
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