KROK 1 2009 – Question 137 · KROK (Medicine) · Pathomorphology

A stillborn child was found to have thickened skin resembling of the tortoise shell, underdeveloped auricles. Histological examination of skin revealed hyperkeratosis, atrophy of the granular epidermis layer; inflammatory changes were not present. What is the most likely diagnosis?

  1. A. Leukoplakia
  2. B. Dermatomyositis
  3. C. Xerodermia
  4. D. Erythroplakia
  5. E. Ichthyosis
Hint

Consider whether the skin change is congenital and non-inflammatory, and what a thick horny layer with a thin granular layer says about keratinisation.

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