KROK 1 2010 – Question 28 · KROK (Medicine) · Pathomorphology

A patient who has been abusing tobacco smoking for a long time has got cough accompanied by excretion of viscous mucus; weakness after minor physical stress, pale skin. The patient has also lost 12,0 kg of body weight. Endoscopic examination of biopsy material his illness was diagnosed as squamous cell carcinoma. Name a pathological process that preceded formation of the tumour:

  1. A. Necrosis
  2. B. Hypoplasia
  3. C. Metaplasia
  4. D. Sclerosis
  5. E. Hyperplasia
Hint

Think about the adaptive change that the bronchial lining undergoes under years of chronic irritation, and how it relates to the cell type of the later tumour.

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