KROK 1 2009 – Question 126 · KROK (Medicine) · Pathomorphology
Autopsy of a 49-year-old woman who died from chronic renal insufficiency, revealed: kidneys were dense, reduced, multicoloured, with haemorrhagic areas. Microscopic examination revealed some hematoxylin bodies in the nuclei of the renal tubule epithelium; "wire-loop" thickening of the glomerular capillary basement membrane; here and there in the capillaries some hyaline thrombi and foci of fibrinoid necrosis were present. What is the most likely diagnosis?
- A. Atherosclerotic nephrosclerosis
- B. Rheumatism
- C. Amyloidosis
- D. Systemic lupus erythematosus
- E. Arteriosclerotic pneumosclerosis
Hint
Think about which disease the combination of nuclear inclusions in the cells and thickened glomerular capillary walls is characteristic of, rather than any single finding.
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