KROK 1 2009 – Question 85 · KROK (Medicine) · Pharmacology
A patient suffering from coronary artery disease had taken a certain drug many times a day in order to arrest stenocardia attacks. Overdose of this drug finally caused intoxication. Objectively: cyanotic skin and mucous membranes, dramatic fall in the arterial pressure, tachycardia, respiration inhibition. Blood has increased concentration of methemoglobin. The drug the patient had taken relates to the following group:
- A. Adenosine drugs
- B. Calcium channel blockers
- C. Organic nitrates
- D. α-adrenoceptor blockers
- E. Myotropic spasmolytics
Hint
Ask which class of anti-anginal drugs generates oxidising metabolites that convert haemoglobin iron to its ferric form when taken in large amounts.
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