KROK 1 2009 – Question 135 · KROK (Medicine) · Pharmacology

In spite of treatment with cardiotonics and thiazide diuretic a patient suffering from chronic cardiac failure still presents with edemata and faces a risk of ascites. What medication should be administered in order to increase the diuretic effect of the above mentioned drugs?

  1. A. Clopamide
  2. B. Spironolactone
  3. C. Manithol
  4. D. Furosemide
  5. E. Amiloride
Hint

Consider which hormonal mechanism keeps sodium and water retained in chronic heart failure despite a thiazide, and which drug class would interrupt it.

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