KROK 1 2009 – Question 140 · KROK (Medicine) · Pharmacology

Depressions and emotional insanities result from the deficit of noradrenalin, serotonin and other biogenic amines in the brain. Their concentration in the synapses can be increased by means of the antidepressants that inhibit the following enzyme:

  1. A. L-amino-acid oxidase
  2. B. Monoamine oxidase
  3. C. Diamine oxidase
  4. D. D-amino-acid oxidase
  5. E. Phenylalanine-4-monooxygenase
Hint

Think about which enzymatic step inactivates the neurotransmitters named in the stem, and how blocking it would change their level in the synapse.

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