KROK 1 2009 – Question 76 · KROK (Medicine) · Pathomorphology

Microscopical examination of an enlarged cervical lymph node revealed blurring of its structure, absence of lymphoid follicles; all the microscopic fields showed cells with roundish nuclei and thin limbus of basophil cytoplasm. It is known from the clinical data that other groups of lymph nodes are also enlarged as well as spleen and liver. What disease might be suspected?

  1. A. Lymphosarcoma
  2. B. Lymphoid leukosis
  3. C. Multiple myeloma
  4. D. Lymphogranulomatosis
  5. E. Myeloid leukosis
Hint

Ask whether a monotonous small round-cell infiltrate with enlarged nodes, spleen and liver is a localised tumour or a systemic proliferation, and of which cell lineage.

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