KROK 1 2007 – Question 13 · KROK (Medicine) · Pathomorphology

Autopsy of a 58 y.o. man revealed that bicuspid valve was deformed, thickened and unclosed. Microscopically: foci of collagen fibrilla are eosinophilic, react positively to fibrin. The most probably it is:

  1. A. Hyalinosis
  2. B. Mucoid swelling
  3. C. Fibrinous inflammation
  4. D. Amyloidosis
  5. E. Fibrinoid swelling
Hint

Collagen that becomes intensely eosinophilic and gives the staining reactions of fibrin signals a deep, irreversible disorganization of connective tissue, typical of rheumatic heart disease.

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