KROK 1 2008 – Question 167 · KROK (Medicine) · Microbiology, Virology, and Immunology
A 30 year old woman has applied a lipstick with a fluorescent substance for a long time. Then she got a limited erythema and slight peeling on her lip border, later there appeared transversal striae and cracks. Special methods of microscopic examination of the affected area helped to reveal sensibilized lymphocytes and macrophages in the connective tissue; cytolysis. What type of immunological hypersensitivity was developed?
- A. IV type (cellular cytotoxicity)
- B. III type (immune complex cytotoxicity)
- C. I type (reaginic)
- D. Granulomatosis
- E. II type (antibody cytotoxicity)
Hint
Notice that the lesion developed slowly after prolonged contact and that microscopy shows sensitised lymphocytes and macrophages; consider which arm of immunity this involves.
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