KROK 1 2008 – Question 36 · KROK (Medicine) · Pathophysiology
A 44 year old woman complains of general weakness, heart pain, significant increase of body weight. Objectively: moon face, hirsutism, AP is 165/100 mm Hg, height - 164 cm, weight - 103 kg; the fat is mostly accumulated on her neck, thoracic girdle, belly. What is the main pathogenetic mechanism of obesity?
- A. Reduced production of thyroid hormones
- B. Increased production of glucocorticoids
- C. Reduced glucagon production
- D. Increased mineralocorticoid production
- E. Increased insulin production
Hint
Moon face, hirsutism, hypertension and fat on the neck and trunk suggest overactivity of one adrenal zone; think about which hormone class shifts fat to the centre of the body.
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