KROK 1 2008 – Question 47 · KROK (Medicine) · Pathomorphology

Histological examination of a skin tissue sampling revealed granulomas consisting of macrophagal nodules with lymphocytes and plasmatic cells. There are also some big macrophages with fatty vacuoles containing causative agents of a disease packed up in form of spheres (Virchow’s cells). Granulation tissue is well vascularized. What disease is this granuloma typical for?

  1. A. Lepra
  2. B. Glanders
  3. C. Syphilis
  4. D. Rhinoscleroma
  5. E. Tuberculosis
Hint

Compare the cell make-up of this granuloma (foamy macrophages packed with bacilli, lymphocytes, plasma cells, no caseation) with the typical granuloma of each listed disease.

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