KROK 1 2023 – Question 28 · KROK (Medicine) · Pathomorphology
A patient with a suspected systemic disease underwent a biopsy of an area of increased density and immobility in the skin. In the dermis, the study detected all types of connective tissue disorganization with a weak cellular reaction, gross sclerosis, and hyalinosis. What disease can be characterized by these pathological changes?
- A. Scleroderma
- B. Polyarteritis nodosa
- C. Dermatofibroma
- D. Psoriasis
- E. Systemic lupus erythematosus
Hint
Consider a systemic connective-tissue disease in which fibrosis with little inflammation makes the skin hard and immobile, with widespread sclerosis and hyalinosis.
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