KROK 1 2020 – Question 91 · KROK (Medicine) · Microbiology, Virology, and Immunology
A 5-year-old child is diagnosed with Bruton’s disease (X-linked agammaglobulinemia) that manifests itself in severe clinical course of bacterial infections and absence of B lymphocytes and plasma cells. What changes of immunoglobulin content can be observed in blood serum of the child with immunodeficiency?
- A. Decreased IgA, IgM
- B. Decreased IgD, IgE
- C. Increased IgA, IgM
- D. Increased IgD, IgE
- E. No changes
Hint
Ask what happens to the serum antibody classes when plasma cells, the cells that secrete them, cannot develop, and which classes are normally the most abundant.
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