KROK 1 2020 – Question 89 · KROK (Medicine) · Pharmacology

A patient used an indirect-acting adrenergic agonist to treat rhinitis. After the patient has been administering in the nose drops for several days, the vasoconstrictive effect of the drug gradually diminished. Name this phenomenon:

  1. A. Tachyphylaxis
  2. B. Allergy
  3. C. Cumulation
  4. D. Teratogenicity
  5. E. Idiosyncrasy
Hint

Consider what happens to the neurotransmitter stores that an indirect-acting drug releases when the drug is applied again and again at short intervals.

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