KROK 1 2020 – Question 110 · KROK (Medicine) · Pharmacology

The mother of a 2-year-old child came to the dentist. During her pregnancy she was randomly taking antibiotics to treat an infectious disease. Examination of the child revealed destruction of the incisors, yellow enamel, and a brown border near the dental cervices. What medicine has a marked teratogenic effect?

  1. A. Ampiox (Ampicillin + Oxacillin)
  2. B. Doxycycline
  3. C. Xantinol nicotinate
  4. D. Furosemide
  5. E. Octadine (Guanethidine)
Hint

Separate the antibiotics from the other drugs, then think about which group of antibiotics is unsafe in pregnancy because of effects on tissues that are being mineralized.

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