KROK 1 2020 – Question 54 · KROK (Medicine) · Pathomorphology

Histology of the liver of a deceased, who was an injection drug user, revealed the following: hydropic degeneration of hepatocytes, ground glass hepatocytes, acidophilic Councilman bodies, lymphocytic-macrophageal infiltrations in the portal tracts. What is the most likely etiology of this disease?

  1. A. Toxic
  2. B. Fungal
  3. C. Bacterial
  4. D. Parasitic
  5. E. Viral
Hint

Consider what the cytoplasmic change and the cell-death pattern in the hepatocytes, with a mononuclear portal infiltrate, suggest about the class of agent, and what the injection route adds.

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