KROK 1 2020 – Question 17 · KROK (Medicine) · Pharmacology
A patient has severe peripheral edema. Consecutive administration of dichlothiazide (hydrochlorothiazide), etacrynic acid, and furosemide did not have any significant diuretic effect. In the blood there is a significant increase of aldosterone levels. What is the drug of choice in this case?
- A. Triamterene
- B. Amiloride
- C. Spironolactone
- D. Mannitol
- E. Metoclopramide
Hint
Ask what the raised aldosterone is doing in the distal nephron and which kind of diuretic interrupts that mechanism rather than repeating the sites already tried.
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