KROK 1 2019 – Question 172 · KROK (Medicine) · Pathophysiology
An 11-year-old girl is brought to the doctor’s office by her mother who states her daughter has been weak with swollen face for 3 days. The mother states her daughter had always been healthy and active until the initiation of symptoms. Upon inquiry, the girl describes a foamy appearance of her urine but denies blood in urine, urinary frequency at night, or pain during urination. Physical examination reveals generalized swelling of the face and pitting edema on the lower limbs. Laboratory study shows proteinuria and microscopic hematuria. Which of the following is the most likely cause of findings in the laboratory study of urine?
- A. Increased permeability across the glomerular capillary wall
- B. Increased glomerular hydrostatic pressure
- C. Increased hydrostatic pressure in Bowman’s capsule
- D. Increased plasma oncotic pressure
- E. -
Hint
Think about what normally keeps plasma proteins and red cells out of the filtrate and what kind of change could let them pass, as opposed to merely changing how much fluid is filtered.
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