KROK 1 2018 – Question 191 · KROK (Medicine) · Pharmacology

During pregnancy a woman has been taking an antiepileptic drug - sodium valproate. It resulted in her child developing a vertebral column malformation - spina bifida. Name the described effect of the drug:

  1. A. Immunosuppressive effect
  2. B. Teratogenic effect
  3. C. Acquired tolerance
  4. D. Dependence
  5. E. Sensitizing effect
Hint

Identify the type of drug effect from the timing and the outcome: exposure during gestation and a structural defect in the child.

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