KROK 1 2019 – Question 16 · KROK (Medicine) · Pharmacology
A patient with peptic ulcer disease was prescribed famotidine. As a result his gastric juice acidity significantly decreased. What is the mechanism of action of this drug?
- A. Histamine H1 receptor blockade
- B. Inhibition of H+, K+-ATPase activity
- C. Histamine H2 receptor blockade
- D. Blockade of histamine receptors in the sympathetic ganglia
- E. Muscarinic M1 receptor blockade
Hint
Think about which upstream stimulus of the acid-producing parietal cell famotidine interrupts, and which subtype of its target sites matters in the stomach.
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