KROK 1 2018 – Question 90 · KROK (Medicine) · Microbiology, Virology, and Immunology

A toxin neutralized with 0.4% formaldehyde under 37-40° C for 4 weeks is used for vaccination. This preparation was first used by Gaston Ramon for diphtheria prevention. Name this preparation:

  1. A. Antitoxic serum
  2. B. Immunoglobulin
  3. C. Inactivated vaccine
  4. D. Anatoxin
  5. E. Adjuvant
Hint

Think about what formaldehyde does to the toxicity and the immunogenicity of a bacterial toxin, and what kind of immunity such a product is meant to induce.

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