KROK 1 2018 – Question 120 · KROK (Medicine) · Microbiology, Virology, and Immunology

A 5-year-old child is diagnosed with Bruton syndrome (X-linked agammaglobulinemia) that manifests itself as severe clinical course of bacterial infections and absence of B lymphocytes and plasma cells. What changes of immunoglobulin content can be observed in blood serum of the child with immunodeficiency?

  1. A. No changes
  2. B. Decreased IgD, IgE
  3. C. Increased IgA, IgM
  4. D. Increased IgD, IgE
  5. E. Decreased IgA, IgM
Hint

Think about which cells produce antibodies, and what the absence of those cells does to the serum levels of the immunoglobulin classes.

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