KROK 1 2017 – Question 107 · KROK (Medicine) · Microbiology, Virology, and Immunology
A 5-year-old child is diagnosed with Bruton syndrome (X-linked agammaglobulinemia) that manifests itself in severe clinical course of bacterial infections and absence of B lymphocytes and plasma cells. What changes of immunoglobulin content can be observed in blood serum of the child with immunodeficiency?
- A. Increased IgA, IgM
- B. Decreased IgA, IgM
- C. Decreased IgD, IgE
- D. No changes
- E. Increased IgD, IgE
Hint
Think about which cell lineage is missing, what that lineage normally secretes, and what you would therefore expect to find in the serum overall.
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