KROK 1 2017 – Question 88 · KROK (Medicine) · Pathomorphology
A 7-year-old boy died of acute posthemorrhagic anemia caused by profuse hemorrhage in the gastrointestinal tract. Postmortem study revealed the following: macroscopically there were acutely enlarged various groups of the lymph nodes, thymomegaly, hepatosplenomegaly, and bright red bone marrow; microscopically there was hypercellular bone marrow with monomorphic infiltrations composed of blasts and diffuse-focal tumor infiltrations in the liver, spleen, lymph nodes, brain substance and tunics. Make the diagnosis:
- A. Acute lymphoblastic leukemia
- B. Acute myeloblastic leukemia
- C. Acute undifferentiated leukemia
- D. Acute monoblastic leukemia
- E. Acute plasmablastic leukemia
Hint
Look at the patient's age, the monomorphic blast infiltrate and the involvement of the thymus and lymph nodes to decide which cell lineage the malignant blasts belong to.
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