KROK 1 2017 – Question 90 · KROK (Medicine) · Pathomorphology
After sensitization a test animal received subcutaneously a dose of antigen. At the site of injection a fibrinous inflammation developed with alteration of vessel walls, basal substance, and fibrous structures of connective tissue. The inflammation took form of mucoid and fibrinoid degeneration, fibrinoid necrosis. What immune response occurred in the test animal?
- A. Granulomatosis
- B. Transplantation immune reaction
- C. Normergic reaction
- D. Immediate hypersensitivity
- E. Delayed hypersensitivity
Hint
Ask which immune mechanism leads to fibrinoid necrosis of vessel walls and connective tissue after a second encounter with the antigen, and what mediates it, cells or antibodies.
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