KROK 1 2017 – Question 56 · KROK (Medicine) · Pharmacology

A patient suffering from gout was prescribed allopurinol. What pharmacological property of allopurinol provides therapeutic effect in this case?

  1. A. Acceleration of nucleic acids synthesis
  2. B. Competitive inhibition of xanthine oxidase
  3. C. Deceleration of pyrimidine nucleotides salvage
  4. D. Acceleration of pyrimidine nucleotides catabolism
  5. E. Acceleration of nitrogen-containing substances excretion
Hint

Think about which step in the breakdown of purines to uric acid a drug could interfere with in order to lower urate production in gout.

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