KROK 1 2017 – Question 83 · KROK (Medicine) · Pharmacology

A woman with polyarticular rheumatoid arthritis was prescribed a non-steroidal antiinflammatory drug - diclofenac sodium. After the patient has been taking it for some time, her concomitant disease exacerbated, which forced the doctor to cancel the prescription of this drug. What concomitant disease could necessitate cancellation of this drug prescription?

  1. A. Essential hypertension
  2. B. Diabetes mellitus
  3. C. Ischemic heart disease
  4. D. Bronchial asthma
  5. E. Ulcer disease
Hint

Think about the adverse effects of cyclooxygenase inhibition and which of these coexisting conditions is most classically worsened by them, forcing withdrawal and not just caution.

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