KROK 1 2016 – Question 145 · KROK (Medicine) · Pharmacology

Local anesthetics (novocaine, lidocaine and others) decreases pain sensitivity of tissues by blocking Na+ and K+ ions from permeating membranes of nerve fibers and endings. Such mechanism of drug action is called:

  1. A. Receptor
  2. B. Direct chemical
  3. C. Enzyme
  4. D. Membrane ionic
  5. E. Antienzyme
Hint

Consider what the anesthetic actually binds to in the nerve fibre and how that kind of target is used to classify mechanisms of drug action.

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