KROK 1 2016 – Question 157 · KROK (Medicine) · Pharmacology

Prescription of penicillin G sodium salt has caused development of neurotoxic effects (hallucinations, convulsions). Such reaction is the result of antagonism with the following neurotransmitter:

  1. A. Serotonin
  2. B. Dopamine
  3. C. GABA
  4. D. Acetylcholine
  5. E. Adenosine
Hint

Think about which transmitter system normally keeps neuronal excitability in check, and how a drug that blocks it could cause seizures at high concentration.

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