KROK 1 2016 – Question 132 · KROK (Medicine) · Pathophysiology

Examination of a 56-year-old woman with a history of type 1 diabetes mellitus revealed a disorder of protein metabolism that is manifested by aminoacidemia in the laboratory blood test values, and clinically by the delayed wound healing and decreased synthesis of antibodies. Which of the following mechanisms causes the development of aminoacidemia?

  1. A. Albuminosis
  2. B. Decrease in the concentration of amino acids in blood
  3. C. Increase in low-density lipoprotein level
  4. D. Increased proteolysis
  5. E. Increase in the oncotic pressure in the blood plasma
Hint

Think about what insulin normally does to protein turnover in muscle and which way that balance shifts when insulin is absent.

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