KROK 1 2016 – Question 144 · KROK (Medicine) · Pathophysiology
What condition may develop 15-30 minutes after re-administration of an antigen as a result of the increased level of antibodies, mainly IgE, that are adsorbed on the surface of target cells, namely tissue basophils (mast cells) and blood basophils?
- A. Antibody-dependent cytotoxicity
- B. Serum sickness
- C. Anaphylaxis
- D. Immune complex hyperresponsiveness
- E. Delayed-type hypersensitivity
Hint
Use the Gell and Coombs classification: ask which type of hypersensitivity depends on IgE fixed to mast cells and how quickly it develops after the second exposure.
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