KROK 1 2015 – Question 153 · KROK (Medicine) · Pathophysiology
A 30-year-old patient’s blood test revealed the following: erythrocyte count is 6 · 10¹²/l, hemoglobin is 10,55 mmol/l. Vaquez’s disease was diagnosed. Name the leading part of pathogenesis:
- A. B12-deficiency
- B. Iron-deficiency
- C. Acidosis
- D. Hypoxia
- E. Neoplastic erythroid hyperplasia
Hint
Consider what drives the red cell mass up in Vaquez’s disease: is the marrow responding to a signal from outside, or has its own regulation of red cell production changed?
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