KROK 1 2015 – Question 104 · KROK (Medicine) · Pharmacology

A patient was prescribed loratadine to treat allergic cheilitis. What is the mechanism of action of this drug?

  1. A. Suppresses activity of choline esterase
  2. B. Suppresses activity of Na+/K+-ATPase
  3. C. Blockade of adrenergic receptors
  4. D. Increases activity of monoamine oxidase
  5. E. Blockade of H1-histamine receptors
Hint

Allergic swelling and itching are driven by a mediator released from mast cells; think about how a second-generation antiallergic drug would interfere with its action.

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