KROK 1 2015 – Question 18 · KROK (Medicine) · Biological Chemistry

A 16-year-old adolescent is diagnosed with hereditary UDP (uridine diphosphate) glucuronyltransferase deficiency. Laboratory tests revealed hyperbilirubinemia caused mostly by increased blood content of the following substance:

  1. A. Unconjugated bilirubin
  2. B. Urobilinogen
  3. C. Conjugated bilirubin
  4. D. Biliverdine
  5. E. Stercobilinogen
Hint

Think about what this enzyme normally does to the pigment in the hepatocyte and which form would therefore pile up when it is missing.

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