KROK 1 2013 – Question 140 · KROK (Medicine) · Microbiology, Virology, and Immunology

A child cut his leg with a piece of glass while playing and was brought to the clinic for the injection of tetanus toxoid. In order to prevent the development of anaphylactic shock the serum was administered by Bezredka method. What mechanism underlies this method of desensitization of the body?

  1. A. Binding of IgE receptors to the mast cells
  2. B. Stimulation of immune tolerance to the antigen
  3. C. Blocking the mediator synthesis in the mast cells
  4. D. Binding of IgE fixed to the mast cells
  5. E. Stimulation of the synthesis of antigen-specific IgG
Hint

Ask what a very small first dose of antigen does to an already sensitised body, so that the full dose that follows is harmless.

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