KROK 1 2013 – Question 119 · KROK (Medicine) · Microbiology, Virology, and Immunology
A patient has been admitted to the infectious diseases department for malaise, fever up to 38°C, jaundice. A few months ago, the patient underwent blood transfusion. The doctor suspected viral hepatitis B. What are the principal methods of laboratory diagnosis of hepatitis B?
- A. Isolation of the virus in laboratory animals (neutralization reaction)
- B. Virus isolation in cell culture and its identification by the cytopathic effects
- C. Detection of virions in blood by electron microscopy
- D. Isolation of the virus in chicken embryos
- E. Serological and gene diagnostics
Hint
Hepatitis B virus is hard to grow in the laboratory, so think about what is practically done to prove the infection by detecting viral components and the body's response.
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