KROK 1 2013 – Question 9 · KROK (Medicine) · Pathophysiology
A 3-year-old boy with pronounced hemorrhagic syndrome doesn’t have antihemophilic globulin A (factor VIII) in the blood plasma. Hemostasis has been impaired at the following stage:
- A. Conversion of prothrombin to thrombin
- B. Internal mechanism of prothrombinase activation
- C. External mechanism of prothrombinase activation
- D. Conversion of fibrinogen to fibrin
- E. Blood clot retraction
Hint
Place factor VIII in the coagulation cascade: ask at which stage it acts and which route of switching on factor X depends on it.
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