KROK 1 2012 – Question 159 · KROK (Medicine) · Pathophysiology
Examination of a 42 year old patient revealed a tumour of adenohypophysis. Objectively: the patient’s weight is 117 kg, he has moon-like hyperemic face, red-blue striae of skin distension on his belly. Osteoporosis and muscle dystrophy are present. AP is 210/140 mm Hg. What is the most probable diagnosis?
- A. Essential hypertension
- B. Conn’s disease
- C. Diabetes mellitus
- D. Cushing’s syndrome
- E. Cushing’s disease
Hint
Trace the hormonal chain: what would a tumour of the anterior pituitary oversecrete, and what would that do to the adrenal cortex?
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