KROK 1 2012 – Question 141 · KROK (Medicine) · Pharmacology

A 66 year old female patient got intravenous injection of magnesium sulfate solution for the purpose of elimination of hypertensive crisis. But arterial pressure didn’t go down and after repeated introduction of the same preparation there appeared sluggishness, slow response, inhibition of consciousness and respiration. What preparation is antagonist of magnesium sulfate and can eliminate symptoms of its overdose?

  1. A. Potassium permanganate
  2. B. Potassium chloride
  3. C. Calcium chloride
  4. D. Sodium chloride
  5. E. Activated carbon
Hint

Magnesium overdose works by opposing the actions of another physiological cation at nerve terminals; ask which ion would compete with it and reverse the block.

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