KROK 1 2012 – Question 135 · KROK (Medicine) · Pharmacology

In spite of treatment with cardiotonics and thiazide diuretic a patient suffering from chronic cardiac failure still presents with edemata and faces a risk of ascites. What medication should be administered in order to increase the diuretic effect of the above mentioned drugs?

  1. A. Manithol
  2. B. Amiloride
  3. C. Clopamide
  4. D. Spironolactone
  5. E. Furosemide
Hint

Think about which neurohormonal system is overactive in chronic cardiac failure and keeps sodium and water retained despite thiazide and cardiotonic therapy.

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