KROK 1 2012 – Question 96 · KROK (Medicine) · Pharmacology

While under barbituric anaesthesia a 65 year old male patient developed respiratory inhibition. Anesthesiologist made him a 10 ml intravenous injection of 0,5% bemegride solution. The patient’s condition got better, the pulmonary ventilation volume increased. What phenomenon underlies the interaction of these medications?

  1. A. Indirect antagonism
  2. B. Direct antagonism
  3. C. Direct synergism
  4. D. Indirect synergism
  5. E. Unilateral antagonism
Hint

Decide whether the second drug opposes the first by acting on the same central structures or by acting elsewhere, and whether the two effects add up or cancel each other.

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