KROK 1 2012 – Question 89 · KROK (Medicine) · Pharmacology

A child suffers from drug idiosyncrasy. What is the cause of such reaction?

  1. A. Associated disease of target organ
  2. B. Hereditary enzymopathy
  3. C. Accumulation of pharmaceutical substance
  4. D. Inhibition of microsomal liver enzymes
  5. E. Exhaustion of substrate interacting with pharmaceutical substance
Hint

Idiosyncrasy is an abnormal response that is not explained by the dose; ask what underlying feature of the individual patient could explain it.

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