KROK 1 2011 – Question 133 · KROK (Medicine) · Pathophysiology

A 35-year-old man developed acute heart failure while running for a long time. What changes in ionic composition can be observed in the cardiac muscle?

  1. A. Reduction of Na+ and Ca2+ ions in the myocardium cells
  2. B. Reduction of K+ and Mg2+ ions in the extracellular space
  3. C. Accumulation of Na+ and Ca2+ ions in the myocardium cells
  4. D. Reduction of Na+ and Ca2+ ions in the extracellular space
  5. E. Accumulation of K+ and Mg2+ ions in the myocardium cells
Hint

Consider how energy shortage in overworked cardiomyocytes affects the membrane pumps, and in which direction each ion then moves across the membrane.

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