KROK 1 2011 – Question 153 · KROK (Medicine) · Pathophysiology

A patient with massive burns developed acute renal insufficiency characterized by a significant and rapid deceleration of glomerular filtration. What is the mechanism of its development?

  1. A. Damage of glomerular filter
  2. B. Reduction of functioning nephron number
  3. C. Renal artery embolism
  4. D. Rise of pressure of tubular fluid
  5. E. Reduction of renal blood flow
Hint

Think about what massive burns do to circulating volume and arterial pressure, and what that does to the driving force for filtration before any kidney tissue is damaged.

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